The series focuses Grey's Anatomy DVD on a group of surgical interns, residents, and the various physicians who serve as their mentors in their professional and personal lives. The show's producers used a "color-blind casting" technique, resulting in a racially diverse cast. Two and a Half Men DVD All roles for Grey's Anatomy are cast without the characters' races being pre-specified, in keeping with creator Shonda Rhimes' vision of diversity. The five characters who are first introduced as interns are Meredith Grey (Ellen Pompeo), Alex Karev (Justin Chambers), George O'Malley (T. R. Knight), Izzie Stevens Weeds DVD (Katherine Heigl) and Cristina Yang (Sandra Oh). They progress to residency after their first year in the surgical program. They are initially mentored by Miranda Bailey (Chandra Wilson), a general surgeon who becomes the hospital's Chief Resident and later becomes an attending general surgeon. The surgical program is run by Chief of Surgery Richard Webber (James Pickens, Jr.) True Blood DVD who has a pre-existing personal relationship with Meredith, having had an affair with her mother when Meredith was a child. In Webber's employ are attending physicians Derek Shepherd (Patrick Dempsey) from New York and Preston Burke (Isaiah Washington), who specialize in neurosurgery and cardiothoracic surgery respectively. Derek is introduced Gossip Girl DVD as Meredith's love interest, while Preston begins a relationship with Cristina.


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